14-3-3 theta Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12588
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14 3 3 tau,14 3 3 theta,14-3-3 protein T-cell,14-3-3 protein tau,14-3-3 protein theta,1433T,1C5,HS1,KCIP1,Protein HS1,Protein kinase C inhibitor protein 1,Protein tau,tyr3/trp5 monooxygenase activation protein,theta,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,theta polypeptide,Ywhaq,YWHAQ抗体 |
| Swissprot | P27348 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human YWHAQ |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:25-1:100; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. In neurons, axonally transported to the nerve terminals. |
| Tissue specificity | Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins.This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs.This gene is upregulated in patients with amyotrophic lateral sclerosis.It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. |
Images
Western Blot analysis of Mouse brain tissue, A549 cell and Human lymphoma tissue, hela cell using 14-3-3 theta Polyclonal Antibody at dilution of 1:950
Immunohistochemistry of paraffin-embedded Human ovarian cancer using 14-3-3 theta Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human lung cancer using 14-3-3 theta Polyclonal Antibody at dilution of 1:50
