(KO Validated) HuR / ELAVL1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1580 / ￥2520 / ￥4020 |
货号：E-AB-60367
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC,IF
Overview
| Synonyms | ELAV1,HUR,Hua,MelG,HuR / ELAVL1,ELAVL1,HuR / ELAVL1抗体 |
| Swissprot | Q15717 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant fusion protein of human HuR / ELAVL1 (NP_001410.2). |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,, 1:500-1:2000;IHC,, 1:100-1:200;IF,, 1:50-1:200; |
| Concentration | 1 mg/mL |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Background | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. |
Images
Western blot analysis of extracts of various cell lines using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts from normal (control) and HuR / ELAVL1 knockout (KO) 293T cells using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse testis using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse kidney using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Rat testis using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
