AATF Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16241
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | AATF,AATF,Apoptosis antagonizing transcription factor ,Apoptosis-antagonizing transcription factor,BFR2,CHE 1,CHE1,DED,Protein AATF,Rb binding protein Che 1,Rb-binding protein Che-1,AATF抗体 |
Swissprot | Q9NY61 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human AATF |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:200-1:1000; |
Concentration | 0.9 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus>nucleolus. |
Tissue specificity | Ubiquitously expressed. Expressed at high levels in brain, heart, kidney, placenta and thymus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. |