ABCB4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19432
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | ABC 21,ABC B4,ABC21,ABCB 4,Abcb4,ABCB4 protein,ATP binding cassette sub family B MDR/TAP member 4,ATP binding cassette sub family B member 4,ATP-binding cassette sub-family B member 4,GBD1,ICP3,MDR 3,MDR2,MDR2/3,MDR3,MDR3 P glycoprotein,MDR3 P gp,MDR3,Multidrug resistance protein 3,Multiple drug resistance 3,P glycoprotein 3 ,P-glycoprotein 3,PFIC 3,PFIC3,PGY 3,PGY3,ABCB4抗体 |
| Swissprot | P21439 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human ABCB4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 2.04mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. |
