ABCD4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12686
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | 69 kDa peroxisomal ABC transporter,ABC 41,ABC41,ABCD 4,ABCD4,ABCD4,ATP binding cassette sub family D (ALD) member 4,ATP binding cassette sub family D member 4,ATP-binding cassette sub-family D member 4,EST352188,MAHCJ,MGC105956,P70R,P79R,Peroxisomal membrane protein 1 like,Peroxisomal membrane protein 1-like,Peroxisomal membrane protein 69,PMP 69,PMP69,PMP70-related protein,PXMP 1L,PXMP1 L,PXMP1-L,PXMP1L,ABCD4抗体 |
| Swissprot | O14678 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human ABCD4 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Peroxisome membrane. |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. |
