ACE1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15454
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | ACE 1,ACE,ACE T,ACE,ACE1,Angiotensin converting enzyme somatic isoform,Angiotensin converting enzyme testis specific isoform,Angiotensin I converting enzyme 1,Angiotensin I converting enzyme,Angiotensin I converting enzyme peptidyl dipeptidase A 1,angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript,Angiotensin-converting enzyme,Carboxycathepsin,CD 143,CD143,CD143 antigen,DCP 1,DCP,DCP1,Dipeptidyl carboxypeptidase 1,Dipeptidyl carboxypeptidase I,Kininase II,MGC26566,MVCD3,Peptidase P,Peptidyl dipeptidase A,soluble form,Testicular ECA,ACE抗体 |
| Swissprot | P12821 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ACE |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:1000-1:5000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Tissue specificity | Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. |
