ACHE Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70015
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | ACEE,ACES,Acetylcholinesterase,AChE,Apoptosis related acetylcholinesterase,ARACHE,N ACHE,N-ACHE,YT,YT blood group,ACHE抗体 |
| Swissprot | P21836,P37136 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse AchE |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:300-1:1000 |
| Concentration | 320 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction, Cell membrane, Membrane, Secreted, Synapse |
| Tissue specificity | Predominates in most expressing tissues except erythrocytes where a glycophospholipid-attached form of ACHE predominates.Highest expression level in medulla oblongata. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission.It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen.Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface.It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits.The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. |
