ACTC1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52617
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | ACTC,ACTC,ACTC1,Actin alpha cardiac muscle 1,Actin,alpha cardiac muscle 1,Alpha-cardiac actin,ASD5,CMD1R,CMH11,LVNC4,ACTC1抗体 |
Swissprot | P68032 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human ACTC1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 1.14mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm>cytoskeleton. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Actins are highly conserved proteins that are involved in various types of cell motility.Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix.Each actin can bind to four others.The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma.The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). |