ACTL6B Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19033
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 53 kDa BRG1 associated factor B,53 kDa BRG1-associated factor B,ACL 6B,ACL6B,ACL6B,Actin like 6,Actin like protein 6B,Actin like protein6B,Actin related protein,Actin related protein Baf53b,actin-like 6B,Actin-like protein 6B,Actin-related protein Baf53b,Actl 6,ACTL 6B,Actl6,ACTL6 B,Actl6b,Arp Na,ArpN a,ArpN alpha,ArpNa,ArpNalpha,Baf 53b,BAF53B,BRG1-associated factor 53B,ACTL6B抗体 |
| Swissprot | O94805 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human ACTL6B |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
| Concentration | 1.74mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins.Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling.This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S.cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression.This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.Alternative splicing results in multiple transcript variants. |
Images
Western blot analysis of Hela and HepG2 cell lysates using ACTL6B Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:100(×200)
