ADGRE3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17906
宿主: Rabbit
反应性: H
应用: WB
Overview
Synonyms | Egf like module containing mucin like hormone receptor like 3,Egf like module containing mucin like receptor 3,EGF like module containing mucin like receptor EMR3,EMR 3,ADGRE3抗体 |
Swissprot | Q9BY15 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human ADGRE3 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.96mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. |