AF/LE Purified Anti-Human CD7 Antibody[HIT7]
规格: | / 50μg / 500μg / 1mg |
价格: | / ¥760 / ¥3160 / ¥4760 |
货号:E-AB-F13150
货期:咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
Synonyms | T-cell antigen CD7;CD7;GP40;T-cell leukemia antigen;T-cell surface antigen Leu-9;TP41;TP41 |
Swissprot | P09564 |
Source | Mouse |
Reactivity | Human |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | HIT7 |
---|---|
Isotype | Mouse IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Background | CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion. |