AF/LE Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7]
| 规格： | / 50μg / 500μg / 1mg |
| 价格： | / ￥760 / ￥3160 / ￥4760 |
货号：E-AB-F10350
货期：咨询
宿主: Armenian Hamster
反应性: M
应用: FCM;Block
Overview
| Synonyms | CD120b;TNF-R2;TNF-RII;TNFR-II;Tnfrsf1b;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;p75;p80 TNF-alpha receptor |
| Swissprot | P25119 |
| Source | Armenian Hamster |
| Reactivity | Mouse |
| Application | FCM;Block |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | TR75-54.7 |
|---|---|
| Isotype | Armenian Hamster IgG |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Background | CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. |
