AF/LE Purified Anti-Mouse CD3 Antibody[17A2]
规格: | / 50μg / 500μg / 1mg |
价格: | / ¥600 / ¥1960 / ¥3560 |
货号:E-AB-F10130
货期:咨询
宿主: Rat
反应性: M
应用: FCM
Overview
Synonyms | CD3;CD3E/D/G/Z;CD3e/d/g/z;T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain |
Swissprot | P04235,P11942,P22646,P24161 |
Source | Rat |
Reactivity | Mouse |
Immunogen | Recombinant Mouse CD3 protein |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 1mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 17A2 |
---|---|
Isotype | Rat IgG2b, κ |
Purification | >98%, Protein A/G purified |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Storage buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method |
Background | CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |