AF/LE Purified Anti-Mouse CD62L Antibody[Mel14]
| 规格： | / 50μg / 500μg / 1mg |
| 价格： | / ￥760 / ￥3160 / ￥4760 |
货号：E-AB-F10110
货期：咨询
宿主: Rat
反应性: M
应用: FCM;Neut
Overview
| Synonyms | CD62L;CD62 antigen-like family member L;L-selectin;LAM-1;LECAM1;Lnhr;Ly-22;Ly22;Lymph node homing receptor;Sell |
| Swissprot | P18337 |
| Source | Rat |
| Reactivity | Mouse |
| Application | FCM;Neut |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | Mel14 |
|---|---|
| Isotype | Rat IgG2a, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Background | CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. |
