AFP Polyclonal Antibody
规格: | / 50μL / 100μL |
价格: | / ¥1010 / ¥1640 |
货号:D-AB-10366L
货期:咨询
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | Afp,AFPD,Alpha fetoglobulin,Alpha fetoprotein,Alpha fetoprotein precursor,Alpha-1-fetoprotein,Alpha-fetoglobulin,Alpha-fetoprotein,alpha-fetoprotein,Hereditary persistence of,included,FETA,FETA,Hereditary persistence of alpha fetoprotein,HPAFP |
Swissprot | P02773 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Rat Afp protein expressed by E.coli |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:300-1:600 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm.Secreted. |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |