AGR2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10036
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | AG 2,AG 2 protein,AG-2,AG2,AG2 protein,AGR 2,AGR2,AGR2,Anterior gradient 2 homolog (Xenopus laevis),anterior gradient 2 homolog,Anterior gradient 2,protein disulphide isomerase family member,Anterior gradient 2,Xenopus,homolog of,Anterior gradient homolog 2,Anterior gradient protein 2 homolog,Epididymis secretory protein Li 116,GOB 4,GOB4,HAG 2,hAG-2,hAG2,HAG2/R,HEL S 116,HPC 8,hPC8,PDIA17,Protein disulfide isomerase family A member 17,secreted cement gland homolog,Secreted cement gland protein XAG 2 homolog,Secreted cement gland protein XAG-2 homolog,Secreted cement gland protein XAG2 homolog,XAG 2,XAG2,AGR2抗体 |
| Swissprot | O95994 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human AGR2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. Endoplasmic reticulum. |
| Tissue specificity | Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Anterior gradient protein 2 homolog (AGR2) is a human protein originally discovered in Xenopus laevis, encoded for by the gene of the same name.In Xenopus AGR2 is an important role in cement gland differentiation, however in human cancer cell lines high levels of AGR2 correlate with reduction of the p53 response and AGR2 levels are elevated in the preneoplastic tissue Barrett's oesophagus. |
