AIF1 Monoclonal Antibody
规格: | / 60μL / 120μL |
价格: | / ¥1420 / ¥2310 |
货号:E-AB-70353
宿主: Mouse
反应性: M,R
应用: IHC
Overview
Synonyms | AIF 1,AIF-1,Aif1,AIF1 protein,AIF1,Allograft inflammatory factor 1,Allograft inflammatory factor 1 splice variant G,allograft inflammatory factor-1 splice variant Hara-1,balloon angioplasty responsive transcription,BART 1,G1,G1 putative splice variant of allograft inflamatory factor 1,IBA 1,IBA1,interferon gamma responsive transcript,Interferon responsive transcript 1,interferon responsive transcript factor 1,Ionized calcium binding adapter molecule 1,Ionized calcium-binding adapter molecule 1,ionized calcium-binding adapter molecule,IRT 1,IRT1,Microglia response factor,MRF1,Protein g1,AIF1抗体 |
Swissprot | O70200 |
Source | Mouse |
Reactivity | Mouse,Rat |
Immunogen | Recombinant protein corresponding to Mouse IBA-1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:200-1:800 |
Concentration | 1.4 mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 5G4E7 |
---|---|
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | This gene is induced by cytokines and interferon.Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma.Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation.Enhances the actin-bundling activity of LCP1.Binds calcium.Plays a role in RAC signaling and in phagocytosis.May play a role in macrophage activation and function.Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.Enhances lymphocyte migration.Plays a role in vascular inflammation. |