AIMP1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19224
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | AIMP 1,Aimp1,AIMP1/p43,AIMP1,Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1,ARS interacting multifunctional protein 1,EMAP 2,EMAP-2,EMAP-II,EMAP2,EMAPII,Endothelial monocyte activating polypeptide 2,Endothelial monocyte activating polypeptide,Endothelial monocyte-activating polypeptide 2,Endothelial monocyte-activating polypeptide II,HLD3,Multisynthase complex auxiliary component p43,Multisynthetase complex auxiliary component p43,OTTHUMP00000219673,p43,Scye 1,Scye1,Scye1,formerly,Small inducible cytokine subfamily E member 1,Small inducible cytokine subfamily E,member 1 (endothelial monocyte-activating),Small inducible cytokine subfamily E,member 1,formerly,AIMP1抗体 |
| Swissprot | Q12904 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human AIMP1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.56mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm>cytosol. Cytoplasmic vesicle>secretory vesicle. Secreted. Endoplasmic reticulum. Golgi apparatus. Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Also secreted in response to hypoxia and both apoptotic and necrotic cell death. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. |
