AIMP2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40046
宿主: Rabbit
反应性: H,R
应用: WB
Overview
| Synonyms | Aimp2,AIMP2,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2,Aminoacyl tRNA synthetase complex interacting multifunctional protein 2,ARS interacting multi functional protein 2,JTV 1,JTV 1 protein,JTV1,JTV1 gene,Multisynthase complex auxiliary component p38,Multisynthetase complex auxiliary component p38,P38,PRO0992,Protein JTV 1,Protein JTV-1,tRNA SYNTHETASE COFACTOR p38,AIMP2抗体 |
| Swissprot | Q13155 |
| Source | Rabbit |
| Reactivity | Human,Rat |
| Immunogen | Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytosol. Nucleus. Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. |
| Tissue specificity | Highest expression level in oocyte |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. |
