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ALOX15 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-16237

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms 15 lipoxygenase 1,15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE,15 LOX,15 LOX 1,15-LOX,15LOX 1,ALOX15,Arachidonate 15 lipoxygenase,Arachidonate 15-lipoxygenase,Arachidonate omega 6 lipoxygenase,Arachidonate omega-6 lipoxygenase,LOG15,LOX15,ALOX15抗体
    Swissprot P16050
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human ALOX15
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm.
    Tissue specificity Detected in monocytes and eosinophils (at protein level). Expressed in airway epithelial cells.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Arachidonate 15-lipoxygenase is an enzyme that in humans is encoded by the ALOX15 gene.Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators.Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE.Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid.May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3.
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