alpha-Fetoprotein/AFP Monoclonal Antibody(Detector)
规格: | |
价格: |
货号:AN006150P
货期:咨询
宿主: Mouse
反应性: H
应用: ELISA Detector
Overview
Synonyms | AFPD;FETA;HPAFP;AFP;Alpha fetoglobulin;Alpha fetoprotein;Alpha fetoprotein precursor;Alpha-1-fetoprotein;Alpha-fetoglobulin;Alpha-fetoprotein;Hereditary persistence of;Hereditary persistence of alpha fetoprotein;included;oralpha fetal protein |
Swissprot | P02771 |
Source | Mouse |
Reactivity | Human |
Immunogen | Recombinant Human alpha-Fetoprotein/AFP Protein expressed by Native Protein |
Application | ELISA Detector |
Recommended dilution | ELISA Detector,,0.1-0.4 μg/mL |
Concentration | 1 mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 4D12 |
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Isotype | IgG1 |
Purification | Protein A/G Purification |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Background | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |