α-SMA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-34268
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p,IF
Overview
| Synonyms | a actin,AAT6,ACTA,ACTA2,Actin alpha 2 smooth muscle aorta,Actin aortic smooth muscle,Actin,aortic smooth muscle,ACTSA,ACTVS,Alpha 2 actin,Alpha actin 2,Alpha cardiac actin,alpha sma,Alpha-actin-2,Cell growth inhibiting gene 46 protein,Cell growth-inhibiting gene 46 protein,GIG46,Growth inhibiting gene 46,MYMY5,ACTC,ACTC,ACTC1,Actin alpha cardiac muscle 1,Actin,alpha cardiac muscle 1,Alpha-cardiac actin,ASD5,CMD1R,CMH11,LVNC4,a actin,Actin alpha skeletal muscle,Actin,actin,alpha 1,skeletal muscle 1,actin,alpha 1,skeletal muscle,Actin,alpha skeletal muscle,actina,actine,ACTS,aktin,Alpha Actin 1,,ASMA,CFTD,CFTD1,CFTDM,MPFD,NEM1,NEM2,NEM3,nemaline myopathy type 3,α-SMA抗体 |
| Swissprot | P62736,P68133,P63267 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from α-SMA |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:500-2000;IHC,,1:50-300;IF,,1:50-1:200 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,actin filament,cytoskeleton,filamentous actin,Cytosol,Extracellular region or secreted,blood microparticle,extracellular exosome,extracellular matrix,extracellular space,Nucleus,Plasma Membrane,Other locations:dense body,focal adhesion,membrane,myelin sheath,myofibril,phagocytic vesicle |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2. |
Images
Western Blot analysis of 3T3, Hela cells using α-SMA Polyclonal Antibody at dilution of 1:1500.
Immunohistochemistry of paraffin-embedded Rat lung tissue using α-SMA Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Mouse heart tissue using α-SMA Polyclonal Antibody at dilution of 1:200.
客户发表文献
- 文献: ADAMTS4-specific MR probe to assess aortic aneurysms in vivo using synthetic peptide libraries
样品类型: aortic wall - 文献: Bioengineering strategies for 3D bioprinting of tubular construct using tissue-specific decellularized extracellular matrix
- 文献: Human Colonoid–Myofibroblast Coculture for Study of Apical Na+/H+ Exchangers of the Lower Cryptal Neck Region
样品类型: colonoids - 文献: Thymol protects against bleomycin-induced pulmonary fibrosis via abrogation of oxidative stress, inflammation, and modulation of miR-29a/TGF-β and PI3K/Akt signaling in mice
样品类型: lung tissues - 文献: Femtosecond laser attenuates oxidative stress, inflammation, and liver fibrosis in rats: Possible role of PPARγ and Nrf2/HO-1 signaling
样品类型: liver - 文献: Silenced SNHG1 Inhibited Epithelial-Mesenchymal Transition and Inflammatory Response of ARPE-19 Cells Induced by High Glucose
样品类型: ARPE-19 cell - 文献: Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts
样品类型: Cell lysate,Tissue homogenate - 文献: Liver fibrosis is a common pathological change in the liver of dairy cows with fatty liver
样品类型: liver - 文献: Changes in Histological Structure, Interleukin 12, Smooth Muscle Actin and Nitric Oxide Synthase 1. and 3. Expression in the Liver of Running and Non-Running Wistar Rats Supplemented with Bee Pollen or Whey Protein
样品类型: liver - 文献: HEG1 as a novel potential biomarker for the prognosis of lung adenocarcinoma
样品类型: Lung cancer tissue - 文献: Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation and differentiation via TGF-β1/Smad and Akt/mTOR pathways
样品类型: tracheal,fibroblasts - 文献: A Combination of Chitosan, Cellulose, and Seaweed Polysaccharide Inhibits Postoperative Intra-abdominal Adhesion in Rats
样品类型: Tissue homogenate - 文献: Protective effect of ethyl acetate fraction of Drynaria quercifolia against CCl4 induced rat liver fibrosis via Nrf2/ARE and NFκB signalling pathway
样品类型: Liver tissue - 文献: Lung histomorphological alterations in rats exposed to cigarette smoke and electronic cigarette vapour
样品类型: lung
