AMPK alpha1 Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22248
宿主: Mouse
反应性: H,M,R
应用: WB,IHC-p
Overview
| Synonyms | 5 AMP activated protein kinase alpha 1catalytic subunit,5 AMP activated protein kinase catalytic alpha 1 chain,5' AMP activated protein kinase catalytic subunit alpha 1,5'-AMP-activated protein kinase catalytic subunit alpha-1,AAPK1,AAPK1,ACACA kinase,acetyl CoA carboxylase kinase,AI194361,AI450832,AL024255,AMP -activate kinase alpha 1 subunit,AMP-activated protein kinase,catalytic,alpha -1,AMPK 1,AMPK alpha 1,AMPK alpha 1 chain,AMPK,AMPK subunit alpha-1,AMPK1,AMPKa1,AMPKalpha1,C130083N04Rik,cb116,EC 2.7.11.1,HMG CoA reductase kinase,HMGCR kinase,hormone sensitive lipase kinase,Hydroxymethylglutaryl CoA reductase kinase,im:7154392,kinase AMPK alpha1,MGC33776,MGC57364,OTTHUMP00000161795,OTTHUMP00000161796,PRKAA 1,PRKAA1,Protein kinase AMP activated alpha 1 catalytic subunit,SNF1-like protein AMPK,SNF1A,Tau protein kinase PRKAA1,wu:fa94c10,AMPKα1 Mouse (9G3)抗体 |
| Swissprot | Q13131 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein of AMPKα1 of PRKAA1 |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | WB 1:1000-2000, IHC 1:100-200 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Cytosol,Nucleus,nuclear speck,nucleoplasm,nucleus,Plasma Membrane,apical plasma membrane,Other locations:cytoplasm,intracellular,nucleotide-activated protein kinase complex |
| Clone No | Clone:9G3 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. |
Images
Western Blot analysis of 1) Hela, 2) Mouse brain , 3) Rat brain using AMPK alpha1 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human lung carcinoma tissue using AMPK alpha1 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human skeletal muscle tissue using AMPK alpha1 Monoclonal Antibody at dilution of 1:200.
