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APLNR Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10156

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms AGTR L1,AGTRL 1,AGTRL1,Angiotensin II receptor like 1,Angiotensin receptor like 1,Angiotensin receptor-like 1,Apelin receptor,APJ (apelin) receptor,APJ,APJ receptor,APJ,APJR,APLNR,B78,FLJ90771,G protein coupled receptor APJ,G-protein coupled receptor APJ,G-protein coupled receptor HG11,GPCR34,HG 11,HG11,HG11 orphan receptor,MGC45246,MSR,msr/apj,APLNR抗体
    Swissprot P35414
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human APLNR
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.4 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Tissue specificity Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
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