APLP1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10047
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1,AMYLOID PRECURSOR-LIKE PROTEIN,Amyloid-like protein 1 precursor,APLP 1,APLP,APLP-1,Aplp1,APLP1,C30,APLP1抗体 |
| Swissprot | P51693 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human APLP1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane and Cytoplasm. C-terminally processed in the Golgi complex. |
| Tissue specificity | Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |
Images
Western Blot analysis of Human fetal brain tissue using APLP1 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human thyroid cancer using APLP1 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human liver cancer using APLP1 Polyclonal Antibody at dilution of 1:25
