ARF6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40035
宿主: Rabbit
反应性: M,R
应用: WB,IHC
Overview
| Synonyms | ADP ribosylation factor 6,ADP ribosylation factor protein 6,ADP-ribosylation factor 6,ARF6,ARF6,DKFZp564M0264,Small GTP binding protein,Small GTPase,ARF6抗体 |
| Swissprot | P62331 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant Mouse ADP-ribosylation factor 6 protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB 1:500-1:1000, IHC 1:50-1:100 |
| Concentration | 2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Golgi apparatus. Cell membrane. Endosome membrane. Cell membrane. Cell projection>filopodium membrane. Recruited to the cell membrane in association with CYTH2 and ARL4C. |
| Tissue specificity | Ubiquitous, with higher levels in heart, substantia nigra, and kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Background | ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily, with 20kda protein size. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF6 is one of best identified ARFs It is present at the plasma membrane and to some extent on endosomal membranes where it regulates the flow of trafficking into and out of the cell and the actin cytoskeleton.This antibody can bind ARFs for the close sequences. |
