ARF6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12250
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ADP ribosylation factor 6,ADP ribosylation factor protein 6,ADP-ribosylation factor 6,ARF6,ARF6,DKFZp564M0264,Small GTP binding protein,Small GTPase,ARF6抗体 |
| Swissprot | P62330 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ARF6 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Golgi apparatus. Cell membrane. Endosome membrane. Cell membrane. Cell projection>filopodium membrane. Recruited to the cell membrane in association with CYTH2 and ARL4C. |
| Tissue specificity | Ubiquitous, with higher levels in heart, substantia nigra, and kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. |
Images
Western Blot analysis of Hela and 293T cell, Mouse liver tissue, A431 and MCF-7 cell using ARF6 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Mouse kidney using ARF6 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain using ARF6 Polyclonal Antibody at dilution of 1:30
