ARHGDIB Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53461
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Arhgdib,D4,D4 GDP dissociation inhibitor,GDIA 2,GDIA2,GDID 4,GDID4,GDIR2,GDP dissociation inhibitor D4,LY GDI,Ly-GDI,LYGDI,MGC108926,RAP1GN1,Rho GDI 2,Rho GDI beta,Rho GDI2,Rho GDP dissociation inhibitor (GDI) beta,Rho GDP dissociation inhibitor 2,Rho GDP dissociation inhibitor beta,Rho GDP-dissociation inhibitor 2,Rho-GDI beta,RhoGDI2,ARHGDIB抗体 |
| Swissprot | P52566 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ARHGDIB |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, cytosol. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them. It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer. |
Images
Western blot analysis of 293T A431 and HepG2 cell lysates using ARHGDIB Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ARHGDIB Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ARHGDIB Polyclonal Antibody at dilution of 1:35(×200)
