ARHGEF11 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16180
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ARHGB,ARHGEF 11,ARHGEF11,DKFZp667F1223,Glutamate transporter EAAT4 associated protein 48,GTRAP 48,GTRAP48,KIAA0380,OTTHUMP00000038716,OTTHUMP00000038717,PDZ RHOGEF,PDZ-RhoGEF,Rho guanine exchange factor (GEF) 11,Rho guanine nucleotide exchange factor (GEF) 11,Rho guanine nucleotide exchange factor 11,RhoA specific guanine nucleotide exchange factor,RhoGEF glutamate transport modulator,ARHGEF11抗体 |
| Swissprot | O15085 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ARHGEF11 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Membrane. Translocated to the membrane upon stimulation. |
| Tissue specificity | Ubiquitously expressed. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. |
Images
Western Blot analysis of Mouse brain tissue using ARHGEF11 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human gastic cancer using ARHGEF11 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human thyroid cancer using ARHGEF11 Polyclonal Antibody at dilution of 1:25
