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ARPC1B Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53178

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms Actin related protein 2/3 complex subunit 1B 41kDa ,Actin related protein 2/3 complex subunit 1B,Actin-related protein 2/3 complex subunit 1B,ARC1B,ARC41,Arp2/3 complex 41 kDa subunit,ARP2/3 protein complex subunit p41 ,Arpc1b,p40 ARC,p41 ARC,p41-Arc,ARPC1B抗体
    Swissprot O15143
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human ARPC1B
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.8mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm>cytoskeleton.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
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