ASAH1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10959
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC,ELISA
Overview
| Synonyms | AC,ACDase,Acid CDase,Acid ceramidase,Acid ceramidase precursor,Acid ceramidase subunit beta,Acylsphingosine deacylase,ASAH 1,ASAH,ASAH1,ASAH1,FLJ21558,FLJ22079,N acylsphingosine amidohydrolase (acid ceramidase) 1,N acylsphingosine amidohydrolase 1,N acylsphingosine amidohydrolase,N-acylsphingosine amidohydrolase,N-acylsphingosine deacylase,PHP,PHP32,Putative 32 kDa heart protein,SMAPME,ASAH1抗体 |
| Swissprot | Q13510 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human ASAH1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | WB 1:1000-1:5000, IHC 1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Lysosome. |
| Tissue specificity | Broadly expressed with highest expression in heart. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. |
Images
Western Blot analysis of Human lung cancer tissue, Human fetal brain and fetal lung tissue using ASAH1 Polyclonal Antibody at dilution of 1:850
Immunohistochemistry of paraffin-embedded Human cervical cancer using ASAH1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer using ASAH1 Polyclonal Antibody at dilution of 1:50
客户发表文献
- 文献: S1P-Induced TNF-α and IL-6 Release from PBMCs Exacerbates Lung Cancer-Associated Inflammation
样品类型: PBMC - 文献: Sphingosine-1-Phosphate Contributes to TLR9-Induced TNF-α Release in Lung Tumor Cells
样品类型: A549 cell - 文献: Intracellular Sphingosine-1-Phosphate Receptor 3 Contributes to Lung Tumor Cell Proliferation
样品类型: lung
