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ASB2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10983

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms Ankyrin repeat and SOCS box 2 containing protein,Ankyrin repeat and SOCS box containing 2,Ankyrin repeat and SOCS box containing protein 2,Ankyrin repeat and SOCS box containing protein 2a,Ankyrin repeat and SOCS box protein 2,Ankyrin repeat containing protein ASB2,ASB 2,ASB2抗体
    Swissprot Q96Q27
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human ASB2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:25-1:100
    Concentration 0.7 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasmic
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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