ASB2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10983
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Ankyrin repeat and SOCS box 2 containing protein,Ankyrin repeat and SOCS box containing 2,Ankyrin repeat and SOCS box containing protein 2,Ankyrin repeat and SOCS box containing protein 2a,Ankyrin repeat and SOCS box protein 2,Ankyrin repeat containing protein ASB2,ASB 2,ASB2抗体 |
Swissprot | Q96Q27 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human ASB2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:25-1:100 |
Concentration | 0.7 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasmic |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |