ASB8 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10961
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Ankyrin repeat and SOCS box containing 8,Ankyrin repeat and SOCS box protein 8,ASB 8,ASB-8,ASB8,ASB8,FLJ21255,MGC5540,OTTHUMP00000237000,OTTHUMP00000237001,OTTHUMP00000237007,OTTHUMP00000237009,OTTHUMP00000237010,PP14212,ASB8抗体 |
| Swissprot | Q9H765 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human ASB8 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas. |
