ASNA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53162
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | ARSA 1,ARSA,ArsA arsenite transporter ATP binding homolog 1,ArsA arsenite transporter,ATP binding,E. coli,homolog of,1,ArsA arsenite transporter,ATP-binding,homolog 1 (bacterial),ARSA I,ARSA-I,ARSA1,ARSAI,Arsenical pump driving ATPase,Arsenical pump-driving ATPase,Arsenical resistance ATPase,Arsenite translocating ATPase,Arsenite transporting ATPase,Arsenite-stimulated ATPase,ASNA 1,ASNA I,ASNA-I,ASNA,ASNA1,Asna1 protein,ASNAI,ATPase ASNA1,GET3,Golgi to ER traffic 3 homolog,hARSA-I,hASNA-I,MGC3821,Transmembrane domain recognition complex 40 kDa ATPase subunit,Transmembrane domain recognition complex,40kDa,TRC40,ASNA1抗体 |
| Swissprot | O43681 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ASNA1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.26mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Endoplasmic reticulum. Nucleus>nucleolus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway. |
