ATF2 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70184
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Activating transcription factor 2,Activating transcription factor 2 splice variant ATF2 var2,ATF 2,Atf-2,Atf2,ATF2 protein,ATF2,cAMP Response Element Binding Protein 2,cAMP response element binding protein CRE BP1,cAMP response element-binding protein CRE-BP1,cAMP responsive element binding protein 2,formerly,cAMP-dependent transcription factor ATF-2,cAMP-responsive element-binding protein 2,CRE BP1,CRE-BP,CREB 2,CREB-2,CREB2,CREBP1,Cyclic AMP dependent transcription factor ATF 2,Cyclic AMP-dependent transcription factor ATF-2,Cyclic AMP-responsive element-binding protein 2,D130078H02Rik,D18875,HB 16,HB16,Histone acetyltransferase ATF2,MGC105211,MGC105222,MGC111558,MGC142504,mXBP,MXBP protein,Tg(Gzma-Klra1)7Wum,TREB 7,TREB7,ATF2抗体 |
| Swissprot | P15336,P16951,Q00969 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ATF2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 490 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Ubiquitously expressed, with more abundant expression in the brain.Highest expression level in endothelial cell. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. |
Images
Immunohistochemistry analysis of paraffin-embedded human lung cancer using ATF2 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using ATF2 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human kidney using ATF2 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded mouse brain using ATF2 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded rat brain using ATF2 Polyclonal Antibody at dilution of 1:400.
