ATP6V1C1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19014
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | ATP6C,ATP6D ,ATP6V1C1,ATPase H+ transporting lysosomal (vacuolar proton pump) 42kD,ATPase H+ transporting lysosomal 42kD V1 subunit C isoform 1,ATPase H+ transporting lysosomal 42kDa V1 subunit C isoform 1,ATPase H+ transporting lysosomal 42kDa V1 subunit C1 ,ATPase H+ transporting lysosomal V1 subunit C1,FLJ20057,H(+) transporting two sector ATPase subunit C,H+ ATPase C subunit ,H+ transporting ATPase chain C vacuolar ,Subunit C of vacuolar proton ATPase V1 domain,V ATPase C subunit ,V ATPase subunit C 1,V-ATPase subunit C 1,V-type proton ATPase subunit C 1,Vacuolar ATP synthase subunit C,Vacuolar proton pump 42 kD subunit ,Vacuolar proton pump C subunit ,Vacuolar proton pump subunit C 1,Vacuolar protonATPase subunit C VI domain ,VATC,VATC1,VATPase C subunit ,VATPase subunit C 1,VMA5,ATP6V1C1抗体 |
Swissprot | P21283 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human ATP6V1C1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:200; |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. |
Images
Western blot analysis of Human cerebella tissue and Human cerebrum tissue lysates using ATP6V1C1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ATP6V1C1 Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ATP6V1C1 Polyclonal Antibody at dilution of 1:100(×200)