ATPIF1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10676
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | ATIF1,ATP synthase inhibitor protein,ATPase inhibitor,ATPase inhibitor mitochondrial,ATPase inhibitor protein,ATPase inhibitory factor 1,ATPI,ATPIF 1,Atpif1,ATPIP,IF(1),IF1,Inhibitor of F(1)F(o)-ATPase,IP,MGC1167,MGC8898,mitochondrial,ATPIF1抗体 |
Swissprot | Q9UII2 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human ATPIF1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
Concentration | 0.2 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | ATPase inhibitor, mitochondrial is an enzyme that in humans is encoded by the ATPIF1 gene.This gene encodes a mitochondrial ATPase inhibitor.Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified.It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient, for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase, possibly by binding at the alpha-beta interface.It is thought to inhibit ATP synthesis by preventing the release of ATP.The inhibitor has two oligomeric states, dimer (the active state) and tetramer. |
Images
Western Blot analysis of Hela, Jurkat, MCF7 and A431 cell using ATPIF1 Polyclonal Antibody at dilution of 1:1200
Immunohistochemistry of paraffin-embedded Human thyroid cancer using ATPIF1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer using ATPIF1 Polyclonal Antibody at dilution of 1:50