ATRIP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18528
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | AGS1,ATIP,ATM and Rad3 related interacting protein,ATM and Rad3-related-interacting protein,ATR interacting protein,ATR-interacting protein,Atrip,ATRIP,DKFZp762J2115,FLJ12343,MGC20625,MGC21482,MGC26740,ATRIP抗体 |
| Swissprot | Q8WXE1 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ATRIP |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Redistributes to discrete nuclear foci upon DNA damage. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes an essential component of the DNA damage checkpoint.The encoded protein binds to single-stranded DNA coated with replication protein A.The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage.Multiple transcript variants encoding different isoforms have been found for this gene. |
