AURKA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19747
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | AIK,ARK-1,ARK1,AURA,Aurka,Aurora 2,Aurora A,Aurora kinase A,Aurora-related kinase 1,Aurora/IPL1 like kinase,Aurora/IPL1-related kinase 1,AURORA2,Breast tumor-amplified kinase,BTAK,hARK1,IAK,IPL1 related kinase,MGC34538,OTTHUMP00000031340,OTTHUMP00000031341,OTTHUMP00000031342,OTTHUMP00000031343,OTTHUMP00000031344,OTTHUMP00000031345,OTTHUMP00000166071,OTTHUMP00000166072,PPP1R47,Protein phosphatase 1,regulatory subunit 47,Serine/threonine kinase 15,Serine/threonine kinase 6,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase aurora-A,STK15,STK6,STK6,STK7,AURKA抗体 |
| Swissprot | O14965 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human AURKA |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 2.3mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytoskeleton>centrosome. Cytoplasm>cytoskeleton>spindle pole. Detected at the neurite hillock in developing neurons (By similarity). Localizes on centrosomes in interphase cells and at each spindle pole in mitosis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. |
