BAK1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10092
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | Apoptosis regulator BAK,BAK,BAK like,Bak NT,BAK,Bak1,Bcl 2 homologous antagonist/killer,Bcl 2 like 7 protein,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7,BCL2 antagonist/killer 1,Bcl2 like 7 Protein,Bcl2-L-7,BCL2L7,CDN1,Cell death inhibitor 1,MGC117255,MGC3887,NBak,Pro apoptotic protein BAK,BAK1抗体 |
| Swissprot | Q16611 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human BAK1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion membrane. |
| Tissue specificity | Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene belongs to the BCL2 protein family.BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.This protein localizes to mitochondria, and functions to induce apoptosis.It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c.This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
Images
Western Blot analysis of Hela, A431, 293T and Jurkat cell using BAK1 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human esophagus cancer using BAK1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer using BAK1 Polyclonal Antibody at dilution of 1:50
