BAK1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70192
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Apoptosis regulator BAK,BAK,BAK like,Bak NT,BAK,Bak1,Bcl 2 homologous antagonist/killer,Bcl 2 like 7 protein,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7,BCL2 antagonist/killer 1,Bcl2 like 7 Protein,Bcl2-L-7,BCL2L7,CDN1,Cell death inhibitor 1,MGC117255,MGC3887,NBak,Pro apoptotic protein BAK,BAK1抗体 |
| Swissprot | Q16611,O08734 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse BAK |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 3.1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion membrane. |
| Tissue specificity | Expressed in a wide variety of tissues, with Highest levels in the heart and skeletal muscle.Highest expression level in mucosa of transverse colon. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
