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Bcl-2 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3580

货号:E-AB-60012

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC,IF

  • 详情
  • 文献(9)
  • Overview

    Synonyms Bcl-2,PPP1R50,BCL2,BCL2抗体
    Swissprot P10415
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen A synthetic peptide of human Bcl-2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),IF
    Recommended dilution WB,, 1:500-1:2000;IHC,, 1:50-1:100;IF,, 1:50-1:100;
    Concentration 1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion outer membrane. Nucleus membrane. Endoplasmic reticulum membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20°C. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3
    Background This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

    客户发表文献

    1. 文献: First Evidence of the Expression and Localization of Prothymosin α in Human Testis and Its Involvement in Testicular Cancers
      样品类型: testicular tissue
    2. 文献: Long-term consumption of fermented pork fat-based diets differing in calorie, fat content, and fatty acid levels mediates oxidative stress, inflammation, redox imbalance, germ cell apoptosis, disruption of steroidogenesis, and testicular dysfunction in Wistar rats
      样品类型: testis tissue
    3. 文献: LncRNA MALAT1 Facilitates Ovarian Cancer Progression through Promoting Chemoresistance and Invasiveness in the Tumor Microenvironment
      样品类型: HTB75 cell,OVCAR3 cell
    4. 文献: Semaphorin 3A attenuates the hypoxia suppression of osteogenesis in periodontal ligament stem cells
      样品类型: Periodontal ligament stem cell (PDLSCs)
    5. 文献: Ethanol increases manganese—Induced spatial learning and memory deficits via oxidative/nitrosative stress induced p53 dependent/independent hippocampal apoptosis
      样品类型: Tissue
    6. 文献: Ethanol Exacerbates Manganese-Induced Neurobehavioral Deficits, Striatal Oxidative Stress, and Apoptosis Via Regulation of p53, Caspase-3, and Bax/Bcl-2 Ratio-Dependent Pathway
      样品类型: Tissue
    7. 文献: The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines
      样品类型: Cell culture supernatant
    8. 文献: Regulated rutin co-administration reverses mitochondrial-mediated apoptosis in Plasmodium berghei-infected mice
      样品类型: Tissue
    9. 文献: Chemopreventive Effects of Onosma mutabilis against Azoxymethane-Induced Colon Cancer in Rats via Amendment of Bax/Bcl-2 and NF-κB Signaling Pathways
      样品类型: colonic tissue
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