beta Tubulin Monoclonal Antibody
规格: | / 30μL / 60μL / 120μL / 300μL / 500μL |
价格: | / ¥295 / ¥548 / ¥875 / ¥1975 / ¥2835 |
货号:E-AB-20095
宿主: Mouse
反应性: H,M,R,Mk,Ch,Dg,Hm,Rb
应用: WB,IHC-p,IP
Overview
Synonyms | beta 3 tubulin,beta-4,CDCBM,CDCBM1,CFEOM3,CFEOM3A,FEOM3,M(beta)3,M(beta)6,MC1R,Neuron specific beta III Tubulin,Neuron-specific class III beta-tubulin,QccE-11995,QccE-15186,TBB3,Tubb 3,TUBB3,TUBB4,Tubulin beta 3,Tubulin beta 3 chain,Tubulin beta 4,Tubulin beta III,Tubulin beta-3 chain,Tubulin beta-4 chain,Tubulin beta-III,β-tubulin抗体 |
Swissprot | Q13509 |
Source | Mouse |
Reactivity | Human,Mouse,Rat,Monkey,Chicken,Dog,Hamster,Rabbit |
Immunogen | Synthetic Peptide |
Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IP |
Recommended dilution | WB 1:500-10000, IHC 1:200, IP 1:200 |
Concentration | 1mg/mL |
Clonality | Monoclonal |
Properties
Cellular localization | Cytoplasm>cytoskeleton. |
Tissue specificity | Expression is primarily restricted to central and peripheral nervous system. |
Clone No | Clone:5L3 |
---|---|
Isotype | IgG |
Purification | Protein A purification |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Background | TUBB3,the class III β tubulin or Tuj1,is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms. |
Images
Western Blot analysis of 1) Hela, 2) Mouse kidney, 3) Rat heart using beta Tubulin Monoclonal Antibody at dilution of 1:5000.
Immunohistochemistry of paraffin-embedded Human colon tissue using beta Tubulin Monoclonal Antibody at dilution of 1:200.
1) Input: Mouse brain tissue, 2) IP product: IP at dilution of 1: 200