BGLAP Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70096
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | BGLAP,BGP,Bone gamma carboxyglutamate (gla) protein,Bone gamma carboxyglutamate gla protein osteocalcin,Bone gamma carboxyglutamate protein,Bone Gla protein,Gamma carboxyglutamic acid containing protein,Gamma-carboxyglutamic acid-containing protein,OC,OCN,OSTCN,Osteocalcin,OTTHUMP00000016586,PMF1,BGLAP抗体 |
| Swissprot | P86546,P04640 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Osteocalcin |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:500 |
| Concentration | 0.84 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | Bone.Highest expression level in bone marrow. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts.In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA.Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues.Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. |
