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BHMT2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18539

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms Betaine homocysteine methyltransferase 2,Betaine homocysteine S methyltransferase 2,EC 2.1.1.5,FLJ20001 ,S methylmethionine homocysteine S methyltransferase BHMT2,SMM hcy methyltransferase,BHMT2抗体
    Swissprot Q9H2M3
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human BHMT2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:5000;IHC,,1:30-1:150;
    Concentration 0.78mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasmic
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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