BHMT2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52473
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Betaine homocysteine methyltransferase 2,Betaine homocysteine S methyltransferase 2,EC 2.1.1.5,FLJ20001 ,S methylmethionine homocysteine S methyltransferase BHMT2,SMM hcy methyltransferase,BHMT2抗体 |
| Swissprot | Q9H2M3 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human BHMT2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Images
Western blot analysis of Human kidney tissue lysate using BHMT2 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using BHMT2 Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using BHMT2 Polyclonal Antibody at dilution of 1:45(×200)
