c-Fms Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15772
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | C FMS,CD 115,CD115,CD115 antigen,CFMS,Colony stimulating factor 1 receptor,Colony stimulating factor I receptor,CSF 1 R,CSF 1R,CSF-1 receptor,CSF-1-R,CSF1 R,CSF1R,CSF1R,CSFR,EC 2.7.10.1,FIM 2,FIM2,FMS,FMS proto oncogene,FMS protooncogene,HDLS,M-CSF Receptor,M-CSF-R,Macrophage colony stimulating factor 1 receptor,Macrophage colony stimulating factor I receptor,Macrophage colony-stimulating factor 1 receptor,McDonough feline sarcoma viral (v fms) oncogene homolog,MCSFR,Oncogen FMS,Proto-oncogene c-Fms,V-FMS McDonough feline sarcoma viral oncogen homolog,formerly,CSF1R抗体 |
| Swissprot | P07333 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CSF1R |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Expressed in bone marrow and in differentiated blood mononuclear cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. |
