c-SRC Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40318
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | ASV,Avian sarcoma virus,c SRC,CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA,cSrc,EC 2.7.10.2,Neuronal CSRC tyrosine specific protein kinase,Neuronal SRC,Oncogene SRC,OTTHUMP00000174476,OTTHUMP00000174477,p60 Src,p60-Src,p60Src,pp60c src,pp60c-src,pp60csrc,Proto oncogene tyrosine protein kinase Src,Proto-oncogene c-Src,Proto-oncogene tyrosine-protein kinase Src,Protooncogene SRC,Protooncogene SRC Rous sarcoma,Src,SRC Oncogene,SRC proto oncogene non receptor tyrosine kinase,SRC,SRC1,Tyrosine kinase pp60c src,Tyrosine protein kinase SRC 1,Tyrosine protein kinase SRC1,v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog,V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian),v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian,c-SRC抗体 |
Swissprot | P12931 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Human Proto-oncogene tyrosine-protein kinase Src protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB 1:1000-1:2000 IHC 1:100-1:300 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Cytoplasm. Cytoskeleton. Mitochondrion. Mitochondrion inner membrane. Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
Background | SRC,also named as SRC1 and p60-Src,belongs to the protein kinase superfamily,Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation,migration,and transformation. In concert with PTK2B,SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase. |
Images
Western Blot analysis of Rat testis and Mouse brain using c-SRC Polyclonl Antibody at dilution of 1:1000.
Western Blot analysis of A431 using c-SRC Polyclonl Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human stomach cancer using c-SRC Polyclonl Antibody at dilution of 1:200.