CALB2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19373
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | 29 kDa calbindin,CAB 29,CAB29,CAL 2,CAL2,CALB 2,CALB2,CALB2,Calbindin 2 29kDa,Calbindin 2,Calbindin D29K,Calbindin2,Calretinin,CR,CALB2抗体 |
Swissprot | P22676 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human CALB2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytosol,Nucleus,Other locations:gap junction,neuron projection,synapse,terminal bouton |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | CALB2 (Calbindin 2) is a Protein Coding gene. Diseases associated with CALB2 include Adenofibroma and Adenomatoid Tumor. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CALB1.This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. |
Images
Western blot analysis of Human fetal brian tissue using CALB2 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CALB2 Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CALB2 Polyclonal Antibody at dilution of 1:25(×200)