CALCOCO1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18858
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | Calcium binding and coiled coil domain 1,CALCOCO1,Calphoglin ,Coiled coil coactivator protein,Coiled coil leucine zipper coactivator 1 ,Coiled coil transcriptional coactivator ,Inorganic pyrophosphatase activator ,KIAA1536 ,PP13275 ,Sarcoma antigen NY-SAR-3,CALCOCO1抗体 |
Swissprot | Q9P1Z2 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human CALCOCO1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
Concentration | 0.84mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. Note: shuttles between nucleus and cytoplasm. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3. |
Images
Western blot analysis of 293T cell and Mouse heart tissue lysates using CALCOCO1 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human tonsil tissue using CALCOCO1 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CALCOCO1 Polyclonal Antibody at dilution of 1:50(×200)